Provera (Medroxyprogesterone)

        The Provera mediation is intended to combat hormone-dependent forms of recurrent breast cancer, recurrent and/or metastatic cancer of the endometrium, kidney.

         The Provera dosage is prescribed by the doctor individually. The drug is intended for oral intake. Tablets should be taken during or immediately after a meal, without chewing, drinking plenty of water. If necessary, tablets can be crushed. 

• Breast cancer in postmenopausal women: 400-1500 mg/day.

• Endometrial cancer and kidney cancer: 100-600 mg/day.

• Metastatic prostate cancer: 100-500 mg/day.

• Anorexia and cachexia syndrome: 1000 mg/day.

• Indications for use

• The Provera pill is used in the following diagnoses:

• cancer cachexia;

• metastatic kidney cancer (except for cancer of the renal pelvis);

• breast cancer;

• endometrial cancer;

• prostate cancer. 

• Hypersensitivity and intolerance to the components of the drug;

• period of pregnancy and lactation;

• tumors of the genital organs or the mammary gland (except in cases of anticancer therapy);

• bleeding of the genital tract for unclear reasons;

• thrombophlebitis, thromboembolism or stroke (increased risk of development or history);

• liver failure;

• hypercalcemia;

• epilepsy;

• a migraine;

• bronchial asthma;

• heart or kidney failure;

• diabetes;

• depressive states. 

When using tablets, the following undesirable effects are possible:

• feeling of depression and sleeplessness;

• dizziness and headache;

• feeling sleepy;

• asthenia;

• abdominal pain;

• the occurrence of discomfort in the epigastrium;

• thrombophlebitis;

• irritability;

• thromboembolism;

• cerebrovascular disorders;

• renal thrombosis;

• insomnia;

• allergic rash and urticaria;

• anaphylaxis;

• hyperthermia;

• alopecia;

• a headache;

• acne and weight loss

• cervical erosion;

• increased nipple sensitivity;

• vaginal discharge (spotting, bloody);

• agalactorrhea;

• impaired glucose tolerance;

• hirsutism;

• moon face;

 Overdose may increase the symptoms described above